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Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
Position Summary:
We are seeking a Senior Manager, Full Stack Software Engineer, to serve as a technical leader in an AI first, agile product environment supporting Global Regulatory Sciences (GRS) technologies. This role is accountable for the end-to-end build and run of AI-native technology assets supporting Global Regulatory Sciences, ensuring solutions are reliable, accessible, secure, compliant, and cost-effective.
The Senior Manager designs, builds, and operates AI native products where large language models, agentic workflows, and data-driven intelligence are the default paradigm-not an addon. The role blends hands-on full-stack engineering, AI product thinking, and operational ownership, with responsibility for both delivery and long-term- sustainability of platforms in a regulated BioPharma environment.
This position provides cross-product technical leadership without direct line management, influencing architecture, shared capabilities, vendor direction, and long-term technical strategy through expertise, collaboration, and hands-on contribution.
Key Responsibilities:
AI Native- Product & Platform Ownership:
Own the build, operation, and continuous improvement of AI native Regulatory applications and platforms, including bespoke solutions and AI-enabled SaaS.
Ensure Regulatory technology assets are stable, secure, compliant, and operationally sound across their lifecycle.
Remain sufficiently hands-on- to design, build, review, and troubleshoot critical components.
Technical Strategy, Architecture & Roadmap:
Develop and maintain an AI-first- Regulatory technology roadmap, guiding build vs. buy decisions, model selection, and platform capabilities aligned to business outcomes.
Define and enforce reference architectures, reusable patterns, and technical guardrails to ensure consistency and quality across products.
Evaluate emerging technologies and delivery models (SaaS / PaaS / IaaS) and influence vendor roadmaps and negotiations to align with enterprise strategy.
Engineering Execution & Operations:
Design, develop, and operate scalable, secure full stack solutions using Python, Java / Node.js, React, REST APIs, and modern cloud-native architectures.
Design and operate Large Language Model LLM native and agentic systems as long-lived products, incorporating human- in- the-loop, monitoring, governance, and continuous improvement.
Build and maintain ML and data pipelines for training, validation, deployment, monitoring, retraining, and rollback.
Implement CI/CD practices and automate workflows across data ingestion, feature engineering, model versioning, and deployment.
Diagnose and resolve complex technical issues, balancing short-term remediation with long-term- architectural strategy.
Product, Stakeholder & Vendor Partnership:
Partner closely with IT Product Managers and GRS stakeholders to plan, prioritize, deliver, and support strategic digital capabilities.
Translate business needs into well designed technical solutions that drive measurable impact in regulatory and operational workflows.
Operate effectively in a highly matrixed organization, aligning stakeholders with differing priorities.
Financial & Operational Stewardship:
Manage and optimize Total Cost of Ownership (build and run) for technology assets, understanding and influencing key cost drivers.
Ensure solutions are cost efficient-, scalable, and sustainable over time.
Required Qualifications & Experience:
6+ years of software engineering experience; BioPharma / Life Sciences experience strongly preferred.
Bachelor’s degree in Computer Science, Software Engineering, Engineering, Life Sciences, or a related quantitative field; advanced degree preferred.
Proven track record delivering complex, production grade- solutions using structured SDLC and Agile product models in regulated environments.
Hands-on experience with developing software and applications that use Large Language Models (LLM) and hands on AI coding with tools such as Codex, Claude Code, OpenAI, etc.
Hands-on experience building Generative and Agentic AI systems using frameworks such as LangChain, LlamaIndex, and enterprise LLM platforms (e.g., OpenAI, AWS Bedrock).
Strong proficiency in Python and React; familiarity with Java, TypeScript, and backend frameworks such as FastAPI.
Experience with AWS cloud services (Lambda, S3, DynamoDB, Bedrock, SageMaker) and event driven, microservices- based- architectures.
Knowledge of Github and source control version management.
Strong data engineering and analytics skills (SQL / NoSQL).
Experience working with vendor partners and offshore development models.
Experience in Regulatory Affairs technologies such as Veeva RIM, Lorenz DocuBridge, Health Authorities Queries (HAQ), or Labeling preferred.
Core Competencies:
Strong technical judgment with the ability to link architecture decisions to business outcomes.
Excellent communication skills across engineering, product, business, and executive audiences.
Ability to execute multiple large initiatives concurrently in an Agile, product centric- model.
Collaborative, pragmatic, and comfortable operating in ambiguity and change.
Innovative mindset with the discipline to deliver reliable, compliant, enterprise -grade solutions.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Compensation Overview:
Madison – Giralda – NJ – US: $135,320 – $163,976
Princeton – NJ – US: $135,320 – $163,976
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:
Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
?Work-life benefits include:
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
*Eligibility Disclosure: T_ _he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science “, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy @type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
Supporting People with Disabilities
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
Candidate Rights
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Data Protection
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.
R1599885 : Senior Manager, Full Stack Software Engineering & Operations Regulatory BI&T Company: BMS
Req Number: R1599885
Updated: 2026-05-31 02:14:28.916 UTC
Location: Madison-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
