Senior Director, Manufacturing Project Manager Full Time NEW

Welcome to an inspired career.

At Halozyme Hypercon™, a wholly-owned subsidiary of Halozyme Therapeutics, Inc., we are reinventing the patient experience and building the future of drug delivery. We are passionate about the important work we do and constantly strive to do more. We embrace transformation and work hard to innovate for the future. We do this together, as One Team – we rise by lifting others up and believe in the power of working together for the collective win. That’s why we need you—to help us make a significant impact by taking on increasingly complex challenges, leaping beyond the status quo, advancing our mission and making our One Team culture thrive.

Join us as Senior Director, Manufacturing Project Manager, and you’ll be part of a culture that welcomes diversity, thinks differently to solve problems, works collaboratively as one team, and delivers meaningful innovations that impact people’s lives.

How You Will Make An Impact

The Senior Director, Manufacturing Project Manager, will be responsible for integrating the planning and execution of complex, multi-stakeholder manufacturing projects from concept through delivery. This role ensures cross-company and cross-functional alignment, managing project risks, and driving execution to meet technical, scheduling, and budget objectives. The ideal candidate is a strong communicator with deep project management expertise and a solid understanding of engineering principles.

In This Role, You’ll Have The Opportunity To

Project Planning & Execution

• Support the development and manage project scopes, schedules, budgets, and risk-mitigation plans for projects associated with Manufacturing.
• Coordinate with contractors, integrators, OEMs, and other internal and external stakeholders to ensure timely and compliant deliverables.
• Provide clear, routine project updates to internal and external stakeholders when required.

Brownfield Site Start-Up & Facility Readiness

• Facilitate the development of the integrated strategy for transforming an existing (brownfield) facility into a GMP-compliant drug product and aseptic fill-finish manufacturing site.
• Collaborate with the project engineer(s) to monitor and report on status utility upgrades, cleanroom retrofits, facility flow improvements, and infrastructure modernization, ensuring readiness for clinical and commercial operations.
• Collaborate with the project engineer(s) to monitor and report on FAT/SAT, commissioning, and qualification of new and refurbished systems and process skids.

Drug Product & Aseptic Fill-Finish Engineering

• Collaborate with the project engineer(s) to monitor and report on installation, qualification, and start-up of aseptic processing equipment, aseptic process flow, material/personnel classification strategies, and contamination control programs and alignment with aseptic processing guidance, and partner-specific requirements.

GMP Compliance, Validation & Documentation

• Monitor and report on commissioning and qualification (IQ/OQ/PQ) activities for utilities, facility areas, equipment, and automation systems.
• Collaborate with Quality to ensure engineering document packages meet GxP requirements, including URS, FRS, FAT/SAT reports, validation protocols, turnover packages, and change controls.

Client & Cross-Functional Collaboration

• Serve as a point of contact for partners utilizing the site’s contract manufacturing services.
• Partner with Manufacturing/MSAT, Quality, and Supply Chain to develop integrated project plans and ensure seamless technology transfer and production readiness.

Financial & Vendor Management

• Manage capital and operational budgets for all activities, including facility renovation, utility upgrades, equipment procurement, and cleanroom construction.
• Support requests for proposals and consolidation of vendor evaluations; help negotiate scope, timelines, and deliverables.
• Support clear executive reporting and decision support for capital investments and trade-offs.

Requirements

To succeed in this role, you’ll need:

• Minimum Master’s degree in Chemical or Mechanical Engineering or related Engineering discipline
• 12–15+ years of experience in CMC or Project Management in biotech or pharmaceutical sterile manufacturing environments.
• Understanding of biologics formulation, sterile manufacturing, and high-concentration product challenges.
• Experience managing external Engineering, Procurement and Construction partners and complex vendor networks a plus.
• Executive-level communication skills with the ability to influence across technical and non-technical teams.
• Experience with monoclonal antibodies, therapeutic proteins, or large-molecule drug manufacturing.
• Background in early-to-commercial scale transitions within emerging biotech companies.
• Experience supporting strategic pharma partnerships and tech transfer models.
• PMP or equivalent certification a plus.

Travel: Travel may be required up to 5% of your time.

In Return, We Offer You

• Full and comprehensive benefit program, including an Employee Stock Purchase Program and 401(k) matching.
• Opportunities to grow in a culture that prioritizes learning, development and progression through in-house programs and tuition reimbursement.
• A collaborative, innovative team that works as one to amplify your impact—on your career, the work you do and patients’ lives.

The most likely base pay range for this position is $214,000-299,250 per year. Several factors, such as experience, tenure, skills, and particular business needs, will determine an individual’s exact level of compensation. Base salary is only one element of employee compensation at Halozyme. Total compensation could include bonuses, sales incentives, and equity awards.

Equal Employment Opportunity Statement

Halozyme Hypercon, Inc is an Equal Employment Opportunity (EEO) employer. It is the policy of the Company to provide equal employment opportunities to all qualified applicants without regard to race (including traits historically associated with race, including but not limited to: hair texture and protective hair styles), religion, religious creed (including religious dress and grooming practices), ethnicity, color, national origin, ancestry, age (40 and older), genetic information, disability (mental and physical, including HIV and AIDS), reproductive health decision-making, medical leave or other types of protected leave, domestic violence victim status, political affiliation, medical condition (including cancer/ genetic characteristics and information), sex, gender, gender identity, gender expression, sexual orientation, marital or familial status, citizenship, pregnancy (including perceived pregnancy, childbirth, breastfeeding, or related medical conditions), military or veteran status, or any other status protected by federal, state, or local law.

Click here to view the Know Your Rights Poster.

Accessibility and Reasonable Accommodations

Halozyme Hypercon is committed to providing reasonable accommodations for qualified individuals with disabilities and disabled veterans during our application process. If you need assistance or an accommodation due to a disability, contact Human Resources at talentacquisition@halozyme.com.

Halozyme Privacy Notice: Applicant Privacy Notice.

To all agencies, please, no phone calls or emails to any employee of Halozyme Hypercon about this requisition. All resumes submitted by search firms/employment agencies to any employee at Halozyme Hypercon via email, the internet, or in any form and method will be deemed the sole property of Halozyme Hypercon unless such search firms/employment agencies were engaged by Halozyme Hypercon for this requisition and a valid agreement with Halozyme Hypercon is in place. If a candidate submitted outside of the Halozyme Hypercon agency engagement process is hired, no fee or payment of any kind will be paid.

Salary Description

$214,000-299,250